Diagnosis and treatment of multiple sclerosis: a review
MP McGinley, CH Goldschmidt, AD Rae-Grant - Jama, 2021 - jamanetwork.com
Importance Multiple sclerosis (MS) is an autoimmune-mediated neurodegenerative disease
of the central nervous system characterized by inflammatory demyelination with axonal
transection. MS affects an estimated 900 000 people in the US. MS typically presents in
young adults (mean age of onset, 20-30 years) and can lead to physical disability, cognitive
impairment, and decreased quality of life. This review summarizes current evidence
regarding diagnosis and treatment of MS. Observations MS typically presents in young …
of the central nervous system characterized by inflammatory demyelination with axonal
transection. MS affects an estimated 900 000 people in the US. MS typically presents in
young adults (mean age of onset, 20-30 years) and can lead to physical disability, cognitive
impairment, and decreased quality of life. This review summarizes current evidence
regarding diagnosis and treatment of MS. Observations MS typically presents in young …