Partial characterization of the enhanced survival of female NZB/W mice treated with lithium chloride
DA Hart, SJ Done, H Benediktsson, SP Lenz - International journal of …, 1994 - Elsevier
Previous investigations have indicated that initiation of LiCl treatment (4 mg/day) of female
NZB/W mice at 10 weeks of age led to enhanced survival of 50% of the mice to> 11 months
of age (Lithium, 3, 61–67, 1992). The present results indicate that this enhancement of
survival is dose dependent in that 2 mg 7 LiCl/day was less effective than 4 mg 7 LiCl/day.
Daily treatment of groups of mice with 2 or 4 mg LiCl per day starting at 8 weeks of age led to
the survival of 40% and 70%, respectively, of the mice at 40 weeks of age, a time when only …
NZB/W mice at 10 weeks of age led to enhanced survival of 50% of the mice to> 11 months
of age (Lithium, 3, 61–67, 1992). The present results indicate that this enhancement of
survival is dose dependent in that 2 mg 7 LiCl/day was less effective than 4 mg 7 LiCl/day.
Daily treatment of groups of mice with 2 or 4 mg LiCl per day starting at 8 weeks of age led to
the survival of 40% and 70%, respectively, of the mice at 40 weeks of age, a time when only …