Defects in neural guidepost structures and failure to remove leptomeningeal cells from the septal midline behind the interhemispheric fusion defects in Netrin1 …
J Hakanen, M Salminen - International Journal of Developmental …, 2015 - Elsevier
Corpus callosum (CC) is the largest commissural tract in mammalian brain and it acts to
coordinate information between the two cerebral hemispheres. During brain development
CC forms at the boundary area between the cortex and the septum and special transient
neural and glial guidepost structures in this area are thought to be critical for CC formation.
In addition, it is thought that the fusion of the two hemispheres in the septum area is a
prerequisite for CC formation. However, very little is known of the molecular mechanisms …
coordinate information between the two cerebral hemispheres. During brain development
CC forms at the boundary area between the cortex and the septum and special transient
neural and glial guidepost structures in this area are thought to be critical for CC formation.
In addition, it is thought that the fusion of the two hemispheres in the septum area is a
prerequisite for CC formation. However, very little is known of the molecular mechanisms …