Effect of persistent versus transient donor-specific HLA antibodies on graft outcomes in pediatric cardiac transplantation
CA Irving, V Carter, AR Gennery, G Parry… - The Journal of Heart and …, 2015 - Elsevier
Background De novo donor-specific HLA antibodies (DSA) are a risk for poor graft
outcomes, but there is little evidence of their long-term effect in pediatric cardiac
transplantation or of the effect of transient versus persistent DSA found using newer antibody
testing methods. Methods Archived serum samples were obtained from patients< 18 years of
age who underwent primary cardiac transplantation during the period from 1996 to 2009.
Luminex antibody testing was performed at 3 months, 6 months and 1 year post-transplant …
outcomes, but there is little evidence of their long-term effect in pediatric cardiac
transplantation or of the effect of transient versus persistent DSA found using newer antibody
testing methods. Methods Archived serum samples were obtained from patients< 18 years of
age who underwent primary cardiac transplantation during the period from 1996 to 2009.
Luminex antibody testing was performed at 3 months, 6 months and 1 year post-transplant …