Factors associated with anti-human leukocyte antigen antibodies in patients supported with continuous-flow devices and effect on probability of transplant and post …
Background One major disadvantage of ventricular assist device (VAD) therapy is the
development of human-leukocyte antigen (HLA) antibodies. We aimed to identify factors
associated with HLA antibodies during continuous flow (CF)-VAD support and assess the
effect on transplant probability and outcomes. Methods We included 143 consecutive heart
failure patients who received a CF-VAD as a bridge-to-transplant at 3 institutions. Factors
associated with post-VAD peak panel reactive antibodies (PRA) among several …
development of human-leukocyte antigen (HLA) antibodies. We aimed to identify factors
associated with HLA antibodies during continuous flow (CF)-VAD support and assess the
effect on transplant probability and outcomes. Methods We included 143 consecutive heart
failure patients who received a CF-VAD as a bridge-to-transplant at 3 institutions. Factors
associated with post-VAD peak panel reactive antibodies (PRA) among several …