The recognition and acceptance of the entity of antibody-mediated rejection (AMR) of solid
organs has been slow to develop. Greatest acceptance and most information relates to
cardiac transplantation. AMR is thought to represent antibody/complement mediated injury
to the microvasculature of the graft that can result in allograft dysfunction, allograft loss,
accelerated graft vasculopathy, and increased mortality. The morphologic hallmark is
microvascular injury with immunoglobulin and complement deposition in capillaries …