Sweating chloride bullets: understanding the role of calcium in eccrine sweat glands and possible implications for hyperhidrosis.

TE Wilson, K Metzler‐Wilson - Experimental dermatology, 2015 - search.ebscohost.com
TE Wilson, K Metzler‐Wilson
Experimental dermatology, 2015search.ebscohost.com
The author discusses the complexity of anoctamin or the novel TMEM16A splice variant
which would have only been expressed in hyperhidrotic skin. The author mentions the
combination of isoforms and the hypotheses that TMEM16A splice variant differences can
lead to different rates of sweating. Also discussed is the root cause of focal hyperhidrosis.
Abstract
The author discusses the complexity of anoctamin or the novel TMEM16A splice variant which would have only been expressed in hyperhidrotic skin. The author mentions the combination of isoforms and the hypotheses that TMEM16A splice variant differences can lead to different rates of sweating. Also discussed is the root cause of focal hyperhidrosis.
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