Severe expression of corpus gastritis is characteristic in gastric cancer patients infected with Helicobacter pylori

S Miehlke, A Hackelsberger, A Meining, R Hatz… - British journal of …, 1998 - nature.com
S Miehlke, A Hackelsberger, A Meining, R Hatz, N Lehn, P Malfertheiner, M Stolte…
British journal of cancer, 1998nature.com
In 50 Helicobacter pylori-infected gastric carcinoma patients the corpus gastritis was
significantly higher than in matched H. pylori-positive control subjects (P< 0.01). Atrophy and
intestinal metaplasia (IM) occurred significantly more often in the antrum of carcinoma
patients (P< 0.01). The odds ratio for gastric carcinoma was 8.85 for high-grade corpus
gastritis and 8.04 when atrophy in the antrum was present.
Abstract
In 50 Helicobacter pylori-infected gastric carcinoma patients the corpus gastritis was significantly higher than in matched H. pylori-positive control subjects (P< 0.01). Atrophy and intestinal metaplasia (IM) occurred significantly more often in the antrum of carcinoma patients (P< 0.01). The odds ratio for gastric carcinoma was 8.85 for high-grade corpus gastritis and 8.04 when atrophy in the antrum was present.
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