Transplanted glial cells migrate over a greater distance and remyelinate demyelinated lesions more rapidly than endogenous remyelinating cells

WF Blakemore, JM Gilson… - Journal of neuroscience …, 2000 - Wiley Online Library
WF Blakemore, JM Gilson, AJ Crang
Journal of neuroscience research, 2000Wiley Online Library
Transplanted glial cells migrate over a greater distance and remyelinate demyelinated
lesions more rapidly than endogenous remye Page 1 Transplanted Glial Cells Migrate Over
a Greater Distance and Remyelinate Demyelinated Lesions More Rapidly Than
Endogenous Remyelinating Cells WF Blakemore, * JM Gilson, and AJ Crang Department of
Clinical Veterinary Medicine, Cambridge, United Kingdom Glial cell transplantation offers a
means of remyelinating areas of demyelination in situations where endogenous …
METHODS
Twenty-seven adult inbred male Lewis rats (at least 250 g) were used in these experiments and glial cell cultures were established from neonatal animals of the same inbred strain of rats. The experimental procedures are illustrated in Figure 1.
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