Decorin, an archetypal member of the small leucine-rich proteoglycan gene family, regulates
collagen fibrillogenesis and cell growth. To further explore its biological function, we
examined the role of Decorin during zebrafish development. Zebrafish Decorin is a
chondroitin sulfate proteoglycan that exhibits a high degree of conservation with its
mammalian counterpart and displays a unique spatiotemporal expression pattern.
Morpholino-mediated knockdown of zebrafish decorin identified a developmental role …