KC/CXCL1 and MIP-2/CXCL2/3 protein levels are markedly elevated during VILI. (a and b) ELISA measurements of (a) KC/CXCL1 protein levels and (b) MIP-2/CXCL2/3 protein levels in lung homogenates from mice placed on either high– or low–peak pressure/stretch ventilator protocol, or from normal nonventilated mice (n = 10 mice per group). *P < 0.02. (c and d) ELISA measurements of (c) KC/CXCL1 protein levels and (d) MIP-2/CXCL2/3 protein levels in plasma from mice placed on either high– or low–peak pressure/stretch ventilator protocol, or from normal nonventilated mice (n = 10 mice per group). P < 0.02.